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George E O Muscat Selected Research

1,3- dihydroxy- 4,4,5,5- tetramethyl- 2- (4- carboxyphenyl)tetrahydroimidazole (NOR 1)

6/2016The Nuclear Receptor, Nor-1, Induces the Physiological Responses Associated With Exercise.
3/2012The nuclear receptor, Nor-1, markedly increases type II oxidative muscle fibers and resistance to fatigue.
6/2005TRAP220 is modulated by the antineoplastic agent 6-Mercaptopurine, and mediates the activation of the NR4A subgroup of nuclear receptors.

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George E O Muscat Research Topics

Disease

11Breast Neoplasms (Breast Cancer)
11/2020 - 08/2006
11Neoplasms (Cancer)
01/2019 - 06/2005
10Obesity
01/2013 - 12/2003
9Insulin Resistance
01/2013 - 12/2003
6Atherosclerosis
01/2016 - 12/2003
6Dyslipidemias (Dyslipidemia)
01/2016 - 09/2005
5Melanoma (Melanoma, Malignant)
02/2017 - 08/2006
4Neoplasm Metastasis (Metastasis)
01/2019 - 02/2013
4Metabolic Diseases (Metabolic Disease)
06/2012 - 10/2005
4Body Weight (Weight, Body)
09/2006 - 10/2002
4Inflammation (Inflammations)
08/2006 - 02/2004
3Weight Gain
11/2013 - 09/2006
3Cardiovascular Diseases (Cardiovascular Disease)
06/2012 - 09/2005
2Glycogen Storage Disease (Glycogenosis)
08/2013 - 06/2012
2Telangiectasis (Telangiectasia)
12/2008 - 02/2004
2Hypotrichosis
12/2008 - 02/2004
2Hypertrophy
11/2006 - 03/2005
1Fibrosis (Cirrhosis)
09/2016
1Chronic Disease (Chronic Diseases)
06/2016
1Carcinogenesis
07/2014
1Chromosomal Instability (Chromosome Stability)
07/2014
1Goiter
06/2014
1Carcinoma (Carcinomatosis)
06/2014
1Papillary Carcinoma
06/2014
1Dosage-sensitive sex reversal
11/2013
1Glycogen Storage Disease Type II (Pompe's Disease)
06/2012
1Type 2 Diabetes Mellitus (MODY)
06/2012
1Wolff-Parkinson-White Syndrome (Wolf-Parkinson-White Syndrome)
06/2012
1Fatigue
03/2012
1Hyperphagia (Overeating)
06/2008
1Hypoxia (Hypoxemia)
06/2008

Drug/Important Bio-Agent (IBA)

14Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
11/2020 - 06/2005
8LipidsIBA
06/2012 - 12/2003
6Glucose (Dextrose)FDA LinkGeneric
11/2013 - 10/2002
5Proteins (Proteins, Gene)FDA Link
01/2019 - 08/2012
5Fatty Acids (Saturated Fatty Acids)IBA
09/2016 - 10/2002
5Messenger RNA (mRNA)IBA
07/2014 - 03/2005
4Hormones (Hormone)IBA
01/2019 - 08/2006
4Transcription Factors (Transcription Factor)IBA
02/2017 - 10/2002
3ChromatinIBA
01/2019 - 01/2017
3Arginine (L-Arginine)FDA Link
01/2019 - 08/2012
3EnzymesIBA
01/2019 - 08/2013
3MethyltransferasesIBA
01/2019 - 06/2012
31,3- dihydroxy- 4,4,5,5- tetramethyl- 2- (4- carboxyphenyl)tetrahydroimidazole (NOR 1)IBA
06/2016 - 06/2005
3RNA (Ribonucleic Acid)IBA
07/2014 - 06/2008
3Insulin (Novolin)FDA Link
11/2012 - 09/2005
3Small Interfering RNA (siRNA)IBA
08/2012 - 04/2009
3Orphan Nuclear ReceptorsIBA
06/2012 - 05/2008
2RetinoidsIBA
11/2020 - 07/2014
2LigandsIBA
11/2020 - 06/2012
2DNA (Deoxyribonucleic Acid)IBA
01/2019 - 01/2017
2Pharmaceutical PreparationsIBA
01/2019 - 01/2017
2Lysine (L-Lysine)FDA Link
01/2019 - 01/2017
2Estrogens (Estrogen)FDA Link
09/2014 - 11/2013
2Histone MethyltransferasesIBA
07/2014 - 08/2013
2Estrogen ReceptorsIBA
07/2014 - 11/2013
2GlycogenIBA
08/2013 - 06/2012
2CholesterolIBA
06/2008 - 12/2003
2Triglycerides (Triacylglycerol)IBA
06/2008 - 08/2004
2HDL CholesterolIBA
03/2005 - 08/2004
1MineralocorticoidsIBA
11/2020
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
11/2020
1Histone Acetyltransferases (Histone Acetyltransferase)IBA
01/2017
1CollagenIBA
09/2016
1Member 1 Group F Nuclear Receptor Subfamily 1IBA
01/2016
1ProgesteroneFDA LinkGeneric
09/2014
1Aromatase (CYP19)IBA
11/2013
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
11/2013
1coactivator-associated arginine methyltransferase 1IBA
08/2013
1TamoxifenFDA LinkGeneric
02/2013
1NexusIBA
01/2013
1OxysterolsIBA
01/2013
1Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA
08/2012
1SteroidsIBA
08/2012
1Biomarkers (Surrogate Marker)IBA
08/2012
1Lipoproteins (Lipoprotein)IBA
07/2012
1AMP-Activated Protein KinasesIBA
06/2012
1CarbohydratesIBA
06/2012
1Mitogen-Activated Protein KinasesIBA
06/2012
1p38 Mitogen-Activated Protein KinasesIBA
06/2012
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
06/2011
1CateninsIBA
06/2011
1beta CateninIBA
04/2009
1PPAR gammaIBA
04/2009
1ThiazolidinedionesIBA
04/2009
1Sterol Regulatory Element Binding Protein 1IBA
06/2008
1Adenosine Triphosphate (ATP)IBA
06/2008
1AzidesIBA
06/2008
1beta Adrenergic ReceptorsIBA
11/2006
1HalofenateIBA
09/2006
1Rosiglitazone (Avandia)FDA Link
09/2006
1AntibodiesIBA
08/2006
1Bromodeoxyuridine (BrdU)IBA
08/2006
1SOXF Transcription FactorsIBA
08/2006
1A-factor (Streptomyces)IBA
01/2006
1NF-KappaB Inhibitor alphaIBA
01/2006
1GW 501516IBA
09/2005

Therapy/Procedure

3Therapeutics
01/2017 - 08/2006
1Glycemic Control
09/2016
1Microspheres (Microsphere)
04/2016